YLR355C

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Systematic name YLR355C
Gene name ILV5
Aliases
Feature type ORF, Verified
Coordinates Chr XII:839253..838066
Primary SGDID S000004347


Description of YLR355C: Bifunctional acetohydroxyacid reductoisomerase and mtDNA binding protein; involved in branched-chain amino acid biosynthesis and maintenance of wild-type mitochondrial DNA; found in mitochondrial nucleoids[1][2][3][4]




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References

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  1. Macierzanka M, et al. (2008) Maintenance and stabilization of mtDNA can be facilitated by the DNA-binding activity of Ilv5p. Biochim Biophys Acta 1783(1):107-17 SGD PMID 18023287
  2. Park S, et al. (2006) Yme2p is a mediator of nucleoid structure and number in mitochondria of the yeast Saccharomyces cerevisiae. Curr Genet 50(3):173-82 SGD PMID 16850347
  3. Petersen JG and Holmberg S (1986) The ILV5 gene of Saccharomyces cerevisiae is highly expressed. Nucleic Acids Res 14(24):9631-51 SGD PMID 3027658
  4. Zelenaya-Troitskaya O, et al. (1995) An enzyme in yeast mitochondria that catalyzes a step in branched-chain amino acid biosynthesis also functions in mitochondrial DNA stability. EMBO J 14(13):3268-76 SGD PMID 7621838

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