YLR350W

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Systematic name YLR350W
Gene name ORM2
Aliases
Feature type ORF, Verified
Coordinates Chr XII:828730..829380
Primary SGDID S000004342


Description of YLR350W: Evolutionarily conserved protein, similar to Orm1p, required for resistance to agents that induce unfolded protein response; Orm1p and Orm2p together control membrane biogenesis by coordinating lipid homeostasis with protein quality control[1][2]




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References

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  1. Han S, et al. (2010) Orm1 and Orm2 are conserved endoplasmic reticulum membrane proteins regulating lipid homeostasis and protein quality control. Proc Natl Acad Sci U S A 107(13):5851-6 SGD PMID 20212121
  2. Hjelmqvist L, et al. (2002) ORMDL proteins are a conserved new family of endoplasmic reticulum membrane proteins. Genome Biol 3(6):RESEARCH0027 SGD PMID 12093374

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