YLR328W
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Systematic name | YLR328W |
Gene name | NMA1 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr XII:784913..786118 |
Primary SGDID | S000004320 |
Description of YLR328W: Nicotinic acid mononucleotide adenylyltransferase; catalyzes the transfer of the adenylyl moiety of ATP to nicotinamide mononucleotide to form NAD; involved in pathways of NAD biosynthesis, including the de novo, NAD(+) salvage, and nicotinamide riboside salvage pathways; NMA1 has a paralog, NMA2, that arose from the whole genome duplication[1][2][3][4]
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References
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- ↑ Anderson RM, et al. (2002) Manipulation of a nuclear NAD+ salvage pathway delays aging without altering steady-state NAD+ levels. J Biol Chem 277(21):18881-90 SGD PMID 11884393
- ↑ Belenky P, et al. (2007) Nicotinamide riboside promotes Sir2 silencing and extends lifespan via Nrk and Urh1/Pnp1/Meu1 pathways to NAD+. Cell 129(3):473-84 SGD PMID 17482543
- ↑ Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 SGD PMID 16169922
- ↑ Emanuelli M, et al. (1999) Identification and characterization of YLR328W, the Saccharomyces cerevisiae structural gene encoding NMN adenylyltransferase. Expression and characterization of the recombinant enzyme. FEBS Lett 455(1-2):13-7 SGD PMID 10428462
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