YLR265C
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Systematic name | YLR265C |
Gene name | NEJ1 |
Aliases | LIF2 |
Feature type | ORF, Verified |
Coordinates | Chr XII:675455..674427 |
Primary SGDID | S000004255 |
Description of YLR265C: Protein involved in regulation of nonhomologous end joining; interacts with DNA ligase IV components Dnl4p and Lif1p; repressed by MAT heterozygosity; regulates cellular distribution of Lif1p[1][2][3][4]
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References
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- ↑ Deshpande RA and Wilson TE (2007) Modes of interaction among yeast Nej1, Lif1 and Dnl4 proteins and comparison to human XLF, XRCC4 and Lig4. DNA Repair (Amst) 6(10):1507-16 SGD PMID 17567543
- ↑ Frank-Vaillant M and Marcand S (2001) NHEJ regulation by mating type is exercised through a novel protein, Lif2p, essential to the ligase IV pathway. Genes Dev 15(22):3005-12 SGD PMID 11711435
- ↑ Kegel A, et al. (2001) Nej1p, a cell type-specific regulator of nonhomologous end joining in yeast. Curr Biol 11(20):1611-7 SGD PMID 11676923
- ↑ Valencia M, et al. (2001) NEJ1 controls non-homologous end joining in Saccharomyces cerevisiae. Nature 414(6864):666-9 SGD PMID 11740566
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