YLR262C

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Systematic name YLR262C
Gene name YPT6
Aliases
Feature type ORF, Verified
Coordinates Chr XII:668891..668244
Primary SGDID S000004252


Description of YLR262C: Rab family GTPase, Ras-like GTP binding protein involved in the secretory pathway, required for fusion of endosome-derived vesicles with the late Golgi, maturation of the vacuolar carboxypeptidase Y; has similarity to the human GTPase, Rab6[1][2][3]




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References

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  1. Lazar T, et al. (1997) Vesicular transport: how many Ypt/Rab-GTPases make a eukaryotic cell? Trends Biochem Sci 22(12):468-72 SGD PMID 9433126
  2. Li B and Warner JR (1996) Mutation of the Rab6 homologue of Saccharomyces cerevisiae, YPT6, inhibits both early Golgi function and ribosome biosynthesis. J Biol Chem 271(28):16813-9 SGD PMID 8663225
  3. Luo Z and Gallwitz D (2003) Biochemical and genetic evidence for the involvement of yeast Ypt6-GTPase in protein retrieval to different Golgi compartments. J Biol Chem 278(2):791-9 SGD PMID 12401784

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