YLR233C

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Systematic name YLR233C
Gene name EST1
Aliases
Feature type ORF, Verified
Coordinates Chr XII:609524..607425
Primary SGDID S000004223


Description of YLR233C: TLC1 RNA-associated factor involved in telomere length regulation as recruitment subunit of telomerase; has G-quadruplex promoting activity that is required for telomere elongation; possible role in activating telomere-bound Est2p-TLC1-RNA[1][2][3]




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References

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  1. Livengood AJ, et al. (2002) Essential regions of Saccharomyces cerevisiae telomerase RNA: separate elements for Est1p and Est2p interaction. Mol Cell Biol 22(7):2366-74 SGD PMID 11884619
  2. Taggart AK and Zakian VA (2003) Telomerase: what are the Est proteins doing? Curr Opin Cell Biol 15(3):275-80 SGD PMID 12787768
  3. Zhang ML, et al. (2010) Yeast telomerase subunit Est1p has guanine quadruplex-promoting activity that is required for telomere elongation. Nat Struct Mol Biol 17(2):202-9 SGD PMID 20098422

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