YLR188W

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Systematic name YLR188W
Gene name MDL1
Aliases
Feature type ORF, Verified
Coordinates Chr XII:528300..530387
Primary SGDID S000004178


Description of YLR188W: Mitochondrial inner membrane half-type ATP-binding cassette (ABC) transporter, mediates export of peptides generated upon proteolysis of mitochondrial proteins, plays a role in the regulation of cellular resistance to oxidative stress[1][2][3][4]




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References

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  1. Chloupkova M, et al. (2003) MDL1 is a high copy suppressor of ATM1: evidence for a role in resistance to oxidative stress. J Mol Biol 331(1):155-65 SGD PMID 12875842
  2. Dean M, et al. (1994) Mapping and sequencing of two yeast genes belonging to the ATP-binding cassette superfamily. Yeast 10(3):377-83 SGD PMID 7912468
  3. Galluhn D and Langer T (2004) Reversible assembly of the ATP-binding cassette transporter Mdl1 with the F1F0-ATP synthase in mitochondria. J Biol Chem 279(37):38338-45 SGD PMID 15247210
  4. Young L, et al. (2001) Role of the ABC transporter Mdl1 in peptide export from mitochondria. Science 291(5511):2135-8 SGD PMID 11251115

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