YLR181C

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Systematic name YLR181C
Gene name VTA1
Aliases
Feature type ORF, Verified
Coordinates Chr XII:517670..516678
Primary SGDID S000004171


Description of YLR181C: Multivesicular body (MVB) protein involved in endosomal protein sorting; regulates Vps4p activity by promoting its oligomerization; has an N-terminal Vps60- and Did2- binding domain, a linker region, and a C-terminal Vps4p binding domain[1][2][3][4][5]




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References

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  1. Azmi I, et al. (2006) Recycling of ESCRTs by the AAA-ATPase Vps4 is regulated by a conserved VSL region in Vta1. J Cell Biol 172(5):705-17 SGD PMID 16505166
  2. Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
  3. Shiflett SL, et al. (2004) Characterization of Vta1p, a class E Vps protein in Saccharomyces cerevisiae. J Biol Chem 279(12):10982-90 SGD PMID 14701806
  4. Xiao J, et al. (2008) Structural basis of vta1 function in the multivesicular body sorting pathway. Dev Cell 14(1):37-49 SGD PMID 18194651
  5. Yeo SC, et al. (2003) Vps20p and Vta1p interact with Vps4p and function in multivesicular body sorting and endosomal transport in Saccharomyces cerevisiae. J Cell Sci 116(Pt 19):3957-70 SGD PMID 12953057

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