YLR133W
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Systematic name | YLR133W |
Gene name | CKI1 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr XII:408445..410193 |
Primary SGDID | S000004123 |
Description of YLR133W: Choline kinase, catalyzing the first step in phosphatidylcholine synthesis via the CDP-choline (Kennedy pathway); exhibits some ethanolamine kinase activity contributing to phosphatidylethanolamine synthesis via the CDP-ethanolamine pathway[1][2][3][4]
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References
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- Jump up ↑ Dowd SR, et al. (2001) Turnover of phosphatidylcholine in Saccharomyces cerevisiae. The role of the CDP-choline pathway. J Biol Chem 276(6):3756-63 SGD PMID 11078727
- Jump up ↑ Hosaka K, et al. (1989) Cloning and characterization of the yeast CKI gene encoding choline kinase and its expression in Escherichia coli. J Biol Chem 264(4):2053-9 SGD PMID 2536698
- Jump up ↑ Kim K, et al. (1999) Isolation and characterization of the Saccharomyces cerevisiae EKI1 gene encoding ethanolamine kinase. J Biol Chem 274(21):14857-66 SGD PMID 10329685
- Jump up ↑ Kim KH, et al. (1998) Expression, purification, and characterization of choline kinase, product of the CKI gene from Saccharomyces cerevisiae. J Biol Chem 273(12):6844-52 SGD PMID 9506987
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