YLR128W

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Systematic name YLR128W
Gene name DCN1
Aliases
Feature type ORF, Verified
Coordinates Chr XII:398530..399433
Primary SGDID S000004118


Description of YLR128W: Scaffold-type E3 ligase required for cullin neddylation and ubiquitin ligase activation; contains a ubiquitin-binding domain (UBA) for ubiquitin and Nedd8 (Rub1p) interaction and a PONY domain involved in cullin binding and neddylation[1][2]




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References

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  1. ↑ Kurz T, et al. (2005) The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae. Nature 435(7046):1257-61 SGD PMID 15988528
  2. ↑ Kurz T, et al. (2008) Dcn1 functions as a scaffold-type e3 ligase for cullin neddylation. Mol Cell 29(1):23-35 SGD PMID 18206966

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