YLR116W
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| Systematic name | YLR116W |
| Gene name | MSL5 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:380822..382252 |
| Primary SGDID | S000004106 |
Description of YLR116W: Component of the commitment complex, which defines the first step in the splicing pathway; essential protein that interacts with Mud2p and Prp40p, forming a bridge between the intron ends; also involved in nuclear retention of pre-mRNA[1][2]
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References
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- ↑ Abovich N and Rosbash M (1997) Cross-intron bridging interactions in the yeast commitment complex are conserved in mammals. Cell 89(3):403-12 SGD PMID 9150140
- ↑ Rutz B and Seraphin B (2000) A dual role for BBP/ScSF1 in nuclear pre-mRNA retention and splicing. EMBO J 19(8):1873-86 SGD PMID 10775271
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