YLR071C

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Systematic name YLR071C
Gene name RGR1
Aliases MED14
Feature type ORF, Verified
Coordinates Chr XII:278626..275378
Primary SGDID S000004061


Description of YLR071C: Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; required for glucose repression, HO repression, RME1 repression and sporulation[1][2][3]




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References

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  1. Li Y, et al. (1995) Yeast global transcriptional regulators Sin4 and Rgr1 are components of mediator complex/RNA polymerase II holoenzyme. Proc Natl Acad Sci U S A 92(24):10864-8 SGD PMID 7479899
  2. Myers LC, et al. (1998) The Med proteins of yeast and their function through the RNA polymerase II carboxy-terminal domain. Genes Dev 12(1):45-54 SGD PMID 9420330
  3. Sakai A, et al. (1990) Structure and molecular analysis of RGR1, a gene required for glucose repression of Saccharomyces cerevisiae. Mol Cell Biol 10(8):4130-8 SGD PMID 2196447

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