YLL006W

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Systematic name YLL006W
Gene name MMM1
Aliases YME6
Feature type ORF, Verified
Coordinates Chr XII:136586..137866
Primary SGDID S000003929


Description of YLL006W: ER integral membrane protein, component of the ERMES complex that links the ER to mitochondria and may promote inter-organellar calcium and phospholipid exchange as well as coordinating mitochondrial DNA replication and growth[1][2][3][4][5]




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References

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  1. Boldogh I, et al. (1998) Interaction between mitochondria and the actin cytoskeleton in budding yeast requires two integral mitochondrial outer membrane proteins, Mmm1p and Mdm10p. J Cell Biol 141(6):1371-81 SGD PMID 9628893
  2. Burgess SM, et al. (1994) MMM1 encodes a mitochondrial outer membrane protein essential for establishing and maintaining the structure of yeast mitochondria. J Cell Biol 126(6):1375-91 SGD PMID 8089172
  3. Hobbs AE, et al. (2001) Mmm1p, a mitochondrial outer membrane protein, is connected to mitochondrial DNA (mtDNA) nucleoids and required for mtDNA stability. J Cell Biol 152(2):401-10 SGD PMID 11266455
  4. Kornmann B, et al. (2009) An ER-mitochondria tethering complex revealed by a synthetic biology screen. Science 325(5939):477-81 SGD PMID 19556461
  5. Meisinger C, et al. (2007) The morphology proteins Mdm12/Mmm1 function in the major beta-barrel assembly pathway of mitochondria. EMBO J 26(9):2229-39 SGD PMID 17410204

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