YKR054C

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Systematic name YKR054C
Gene name DYN1
Aliases DHC1, PAC6
Feature type ORF, Verified
Coordinates Chr XI:547925..535647
Primary SGDID S000001762


Description of YKR054C: Cytoplasmic heavy chain dynein, microtubule motor protein, required for anaphase spindle elongation; involved in spindle assembly, chromosome movement, and spindle orientation during cell division, targeted to microtubule tips by Pac1p[1][2][3][4][5]




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References

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  1. Eshel D, et al. (1993) Cytoplasmic dynein is required for normal nuclear segregation in yeast. Proc Natl Acad Sci U S A 90(23):11172-6 SGD PMID 8248224
  2. Lee WL, et al. (2003) The role of the lissencephaly protein Pac1 during nuclear migration in budding yeast. J Cell Biol 160(3):355-64 SGD PMID 12566428
  3. Li YY, et al. (1993) Disruption of mitotic spindle orientation in a yeast dynein mutant. Proc Natl Acad Sci U S A 90(21):10096-100 SGD PMID 8234262
  4. Saunders WS, et al. (1995) Saccharomyces cerevisiae kinesin- and dynein-related proteins required for anaphase chromosome segregation. J Cell Biol 128(4):617-24 SGD PMID 7860634
  5. Steinberg-Neifach O and Eshel D (2000) Simultaneous expression of both MAT loci in haploid cells suppresses mutations in yeast microtubule motor genes. Mol Gen Genet 264(3):300-5 SGD PMID 11085270

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