YKR042W
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| Systematic name | YKR042W |
| Gene name | UTH1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XI:519527..520624 |
| Primary SGDID | S000001750 |
Description of YKR042W: Mitochondrial outer membrane and cell wall localized SUN family member involved in cell wall biogenesis and required for mitochondrial autophagy; involved in the oxidative stress response, life span during starvation, and cell death[1][2][3][4][5][6][7]
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References
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- ↑ Bandara PD, et al. (1998) Involvement of the Saccharomyces cerevisiae UTH1 gene in the oxidative-stress response. Curr Genet 34(4):259-68 SGD PMID 9799359
- ↑ Camougrand N, et al. (2003) The product of the UTH1 gene, required for Bax-induced cell death in yeast, is involved in the response to rapamycin. Mol Microbiol 47(2):495-506 SGD PMID 12519199
- ↑ Camougrand NM, et al. (2000) The SUN family: UTH1, an ageing gene, is also involved in the regulation of mitochondria biogenesis in Saccharomyces cerevisiae. Arch Biochem Biophys 375(1):154-60 SGD PMID 10683261
- ↑ Kennedy BK, et al. (1995) Mutation in the silencing gene SIR4 can delay aging in S. cerevisiae. Cell 80(3):485-96 SGD PMID 7859289
- ↑ Kissova I, et al. (2004) Uth1p is involved in the autophagic degradation of mitochondria. J Biol Chem 279(37):39068-74 SGD PMID 15247238
- ↑ Ritch JJ, et al. (2010) The Saccharomyces SUN gene, UTH1, is involved in cell wall biogenesis. FEMS Yeast Res 10(2):168-76 SGD PMID 20070376
- ↑ Velours G, et al. (2002) Dual cell wall/mitochondria localization of the 'SUN' family proteins. FEMS Microbiol Lett 207(2):165-72 SGD PMID 11958935
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