YKR029C

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Systematic name YKR029C
Gene name SET3
Aliases
Feature type ORF, Verified
Coordinates Chr XI:499833..497578
Primary SGDID S000001737


Description of YKR029C: Defining member of the SET3 histone deacetylase complex which is a meiosis-specific repressor of sporulation genes; necessary for efficient transcription by RNAPII; one of two yeast proteins that contains both SET and PHD domains[1][2][3]




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References

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  1. Krogan NJ, et al. (2003) Methylation of histone H3 by Set2 in Saccharomyces cerevisiae is linked to transcriptional elongation by RNA polymerase II. Mol Cell Biol 23(12):4207-18 SGD PMID 12773564
  2. Pijnappel WW, et al. (2001) The S. cerevisiae SET3 complex includes two histone deacetylases, Hos2 and Hst1, and is a meiotic-specific repressor of the sporulation gene program. Genes Dev 15(22):2991-3004 SGD PMID 11711434
  3. Wang A, et al. (2002) Requirement of Hos2 histone deacetylase for gene activity in yeast. Science 298(5597):1412-4 SGD PMID 12434058

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