YKR003W

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Systematic name YKR003W
Gene name OSH6
Aliases
Feature type ORF, Verified
Coordinates Chr XI:445381..446727
Primary SGDID S000001711


Description of YKR003W: Member of an oxysterol-binding protein family with overlapping, redundant functions in sterol metabolism and which collectively perform a function essential for viability; GFP-fusion protein localizes to the cell periphery; overexpression extends lifespan by promoting vacuole fusion[1][2][3]




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References

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  1. Beh CT, et al. (2001) Overlapping functions of the yeast oxysterol-binding protein homologues. Genetics 157(3):1117-40 SGD PMID 11238399
  2. Gebre S, et al. (2012) Osh6 overexpression extends the lifespan of yeast by increasing vacuole fusion. Cell Cycle 11(11) SGD PMID 22622083
  3. Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095

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