YKL195W
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| Systematic name | YKL195W |
| Gene name | MIA40 |
| Aliases | FMP15, TIM40 |
| Feature type | ORF, Verified |
| Coordinates | Chr XI:75821..77032 |
| Primary SGDID | S000001678 |
Description of YKL195W: Essential protein of the mitochondrial intermembrane space (IMS); promotes retention of newly imported proteins; may do so by stabilizing client protein folding as part of a disulfide relay system or transferring metal to client proteins[1][2][3]
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References
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- ↑ Chacinska A, et al. (2004) Essential role of Mia40 in import and assembly of mitochondrial intermembrane space proteins. EMBO J 23(19):3735-46 SGD PMID 15359280
- ↑ Mesecke N, et al. (2005) A disulfide relay system in the intermembrane space of mitochondria that mediates protein import. Cell 121(7):1059-69 SGD PMID 15989955
- ↑ Terziyska N, et al. (2005) Mia40, a novel factor for protein import into the intermembrane space of mitochondria is able to bind metal ions. FEBS Lett 579(1):179-84 SGD PMID 15620710
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