YKL172W
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| Systematic name | YKL172W |
| Gene name | EBP2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XI:125759..127042 |
| Primary SGDID | S000001655 |
Description of YKL172W: Required for 25S rRNA maturation and 60S ribosomal subunit assembly; localizes to the nucleolus and in foci along nuclear periphery; constituent of 66S pre-ribosomal particles; cooperates with Rrs1p and Mps3p to mediate telomere clustering by binding Sir4p, but is not involved in telomere tethering[1][2][3][4]
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References
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- ↑ Horigome C, et al. (2011) Ribosome biogenesis factors bind a nuclear envelope SUN domain protein to cluster yeast telomeres.LID - 10.1038/emboj.2011.267 [doi] EMBO J () SGD PMID 21822217
- ↑ Horsey EW, et al. (2004) Role of the yeast Rrp1 protein in the dynamics of pre-ribosome maturation. RNA 10(5):813-27 SGD PMID 15100437
- ↑ Huber MD, et al. (2000) The budding yeast homolog of the human EBNA1-binding protein 2 (Ebp2p) is an essential nucleolar protein required for pre-rRNA processing. J Biol Chem 275(37):28764-73 SGD PMID 10849420
- ↑ Tsujii R, et al. (2000) Ebp2p, yeast homologue of a human protein that interacts with Epstein-Barr virus nuclear antigen 1, is required for pre-rRNA processing and ribosomal subunit assembly. Genes Cells 5(7):543-53 SGD PMID 10947841
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