YKL119C

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Systematic name YKL119C
Gene name VPH2
Aliases CLS10, VMA12
Feature type ORF, Verified
Coordinates Chr XI:219217..218570
Primary SGDID S000001602


Description of YKL119C: Integral membrane protein required for vacuolar H+-ATPase (V-ATPase) function, although not an actual component of the V-ATPase complex; functions in the assembly of the V-ATPase; localized to the endoplasmic reticulum (ER)[1][2][3][4]




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References

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  1. Forgac M (1999) Structure and properties of the vacuolar (H+)-ATPases. J Biol Chem 274(19):12951-4 SGD PMID 10224039
  2. Graham LA and Stevens TH (1999) Assembly of the yeast vacuolar proton-translocating ATPase. J Bioenerg Biomembr 31(1):39-47 SGD PMID 10340847
  3. Jackson DD and Stevens TH (1997) VMA12 encodes a yeast endoplasmic reticulum protein required for vacuolar H+-ATPase assembly. J Biol Chem 272(41):25928-34 SGD PMID 9325326
  4. Preston RA, et al. (1992) Genes required for vacuolar acidity in Saccharomyces cerevisiae. Genetics 131(3):551-8 SGD PMID 1628805

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