YKL088W
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Systematic name | YKL088W |
Gene name | CAB3 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr XI:275283..276998 |
Primary SGDID | S000001571 |
Description of YKL088W: Subunit of a phosphopantothenoylcysteine decarboxylase (PPCDC; Cab3p, Sis2p, Vhs3p) complex, which catalyzes the third step of coenzyme A biosynthesis; null mutant lethality is complemented by E. coli coaBC[1][2][3][4]
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References
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- ↑ Hazbun TR, et al. (2003) Assigning function to yeast proteins by integration of technologies. Mol Cell 12(6):1353-65 SGD PMID 14690591
- ↑ Olzhausen J, et al. (2009) Genetic analysis of coenzyme A biosynthesis in the yeast Saccharomyces cerevisiae: identification of a conditional mutation in the pantothenate kinase gene CAB1. Curr Genet 55(2):163-73 SGD PMID 19266201
- ↑ Ruiz A, et al. (2009) Moonlighting proteins Hal3 and Vhs3 form a heteromeric PPCDC with Ykl088w in yeast CoA biosynthesis. Nat Chem Biol 5(12):920-8 SGD PMID 19915539
- ↑ Tatusov RL, et al. (2000) The COG database: a tool for genome-scale analysis of protein functions and evolution. Nucleic Acids Res 28(1):33-6 SGD PMID 10592175
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