YJR144W

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Systematic name YJR144W
Gene name MGM101
Aliases MGM9
Feature type ORF, Verified
Coordinates Chr X:700882..701691
Primary SGDID S000003905


Description of YJR144W: Protein with a role in mitochondrial DNA recombinational repair; binds to and catalyzes the annealing of single-stranded mtDNA; oligomerizes to form rings and filaments; related to Rad52-type recombination proteins, with limited overall similarity but sharing conserved functionally important residues; component of the mitochondrial nucleoid, required for the repair of oxidative mtDNA damage[1][2][3][4]




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References

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  1. Chen XJ, et al. (1993) MGM101, a nuclear gene involved in maintenance of the mitochondrial genome in Saccharomyces cerevisiae. Nucleic Acids Res 21(15):3473-7 SGD PMID 8346025
  2. Mbantenkhu M, et al. (2011) Mgm101 is a Rad52-related protein required for mitochondrial DNA recombination. J Biol Chem () SGD PMID 22027892
  3. Meeusen S, et al. (1999) Mgm101p is a novel component of the mitochondrial nucleoid that binds DNA and is required for the repair of oxidatively damaged mitochondrial DNA. J Cell Biol 145(2):291-304 SGD PMID 10209025
  4. Zuo X, et al. (2007) A functional core of the mitochondrial genome maintenance protein Mgm101p in Saccharomyces cerevisiae determined with a temperature-conditional allele. FEMS Yeast Res 7(1):131-40 SGD PMID 17311591

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