YJR139C
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| Systematic name | YJR139C |
| Gene name | HOM6 |
| Aliases | THR6 |
| Feature type | ORF, Verified |
| Coordinates | Chr X:690524..689445 |
| Primary SGDID | S000003900 |
Description of YJR139C: Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase), dimeric enzyme that catalyzes the third step in the common pathway for methionine and threonine biosynthesis; enzyme has nucleotide-binding, dimerization and catalytic regions[1][2][3]
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References
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- ↑ DeLaBarre B, et al. (2000) Crystal structures of homoserine dehydrogenase suggest a novel catalytic mechanism for oxidoreductases. Nat Struct Biol 7(3):238-44 SGD PMID 10700284
- ↑ Thomas D, et al. (1993) Evolutionary relationships between yeast and bacterial homoserine dehydrogenases. FEBS Lett 323(3):289-93 SGD PMID 8500624
- ↑ Yumoto N, et al. (1991) Rapid purification and characterization of homoserine dehydrogenase from Saccharomyces cerevisiae. Arch Biochem Biophys 285(2):270-5 SGD PMID 1897932
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