YJR135W-A
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| Systematic name | YJR135W-A |
| Gene name | TIM8 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr X:676971..677234 |
| Primary SGDID | S000007348 |
Description of YJR135W-A: Mitochondrial intermembrane space protein, forms a complex with Tim13p that delivers a subset of hydrophobic proteins to the TIM22 complex for inner membrane insertion; homolog of human TIMM8A, implicated in Mohr-Tranebjaerg syndrome[1][2][3][4]
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References
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- ↑ Bauer MF and Neupert W (2001) Import of proteins into mitochondria: a novel pathomechanism for progressive neurodegeneration. J Inherit Metab Dis 24(2):166-80 SGD PMID 11405338
- ↑ Davis AJ, et al. (2007) The Tim9p/10p and Tim8p/13p complexes bind to specific sites on Tim23p during mitochondrial protein import. Mol Biol Cell 18(2):475-86 SGD PMID 17122363
- ↑ Koehler CM, et al. (1999) Human deafness dystonia syndrome is a mitochondrial disease. Proc Natl Acad Sci U S A 96(5):2141-6 SGD PMID 10051608
- ↑ Leuenberger D, et al. (1999) Different import pathways through the mitochondrial intermembrane space for inner membrane proteins. EMBO J 18(17):4816-22 SGD PMID 10469659
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