YJR097W

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Systematic name YJR097W
Gene name JJJ3
Aliases DPH4
Feature type ORF, Verified
Coordinates Chr X:612413..612931
Primary SGDID S000003858


Description of YJR097W: Protein of unknown function, contains a CSL Zn finger and a DnaJ-domain; involved in diphthamide biosynthesis; ortholog human Dph4[1][2][3]




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References

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  1. Liu S, et al. (2004) Identification of the proteins required for biosynthesis of diphthamide, the target of bacterial ADP-ribosylating toxins on translation elongation factor 2. Mol Cell Biol 24(21):9487-97 SGD PMID 15485916
  2. Thakur A, et al. (2012) Structure and mechanistic insights into novel iron-mediated moonlighting functions of human J-protein Cochaperone, Dph4. J Biol Chem () SGD PMID 22367199
  3. Walsh P, et al. (2004) The J-protein family: modulating protein assembly, disassembly and translocation. EMBO Rep 5(6):567-71 SGD PMID 15170475

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