YJR059W

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Systematic name YJR059W
Gene name PTK2
Aliases STK2
Feature type ORF, Verified
Coordinates Chr X:545787..548243
Primary SGDID S000003820


Description of YJR059W: Putative serine/threonine protein kinase involved in regulation of ion transport across plasma membrane; enhances spermine uptake[1][2]




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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [3] [4]





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References

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  1. Erez O and Kahana C (2002) Deletions of SKY1 or PTK2 in the Saccharomyces cerevisiae trk1Deltatrk2Delta mutant cells exert dual effect on ion homeostasis. Biochem Biophys Res Commun 295(5):1142-9 SGD PMID 12135613
  2. Nozaki T, et al. (1996) A second gene encoding a putative serine/threonine protein kinase which enhances spermine uptake in Saccharomyces cerevisiae. Biochem Biophys Res Commun 228(2):452-8 SGD PMID 8920934
  3. Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  4. submitted by Jeff Ubersax on 2004-01-27

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