YJL134W

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Systematic name YJL134W
Gene name LCB3
Aliases LBP1, YSR2
Feature type ORF, Verified
Coordinates Chr X:158188..159417
Primary SGDID S000003670


Description of YJL134W: Long-chain base-1-phosphate phosphatase with specificity for dihydrosphingosine-1-phosphate, regulates ceramide and long-chain base phosphates levels, involved in incorporation of exogenous long chain bases in sphingolipids[1][2][3][4][5]




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References

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  1. Kihara A, et al. (2003) Transmembrane topology of sphingoid long-chain base-1-phosphate phosphatase, Lcb3p. Genes Cells 8(6):525-35 SGD PMID 12786943
  2. Kobayashi SD and Nagiec MM (2003) Ceramide/long-chain base phosphate rheostat in Saccharomyces cerevisiae: regulation of ceramide synthesis by Elo3p and Cka2p. Eukaryot Cell 2(2):284-94 SGD PMID 12684378
  3. Mandala SM, et al. (1998) Sphingoid base 1-phosphate phosphatase: a key regulator of sphingolipid metabolism and stress response. Proc Natl Acad Sci U S A 95(1):150-5 SGD PMID 9419344
  4. Mao C, et al. (1997) Identification and characterization of Saccharomyces cerevisiae dihydrosphingosine-1-phosphate phosphatase. J Biol Chem 272(45):28690-4 SGD PMID 9353337
  5. Qie L, et al. (1997) Identification of a Saccharomyces gene, LCB3, necessary for incorporation of exogenous long chain bases into sphingolipids. J Biol Chem 272(26):16110-7 SGD PMID 9195906

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