YJL125C
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| Systematic name | YJL125C |
| Gene name | GCD14 |
| Aliases | TRM61 |
| Feature type | ORF, Verified |
| Coordinates | Chr X:186679..185528 |
| Primary SGDID | S000003661 |
Description of YJL125C: Subunit of tRNA (1-methyladenosine) methyltransferase, with Gcd10p, required for the modification of the adenine at position 58 in tRNAs, especially tRNAi-Met; first identified as a negative regulator of GCN4 expression[1][2][3]
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References
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- Jump up ↑ Anderson J, et al. (1998) The essential Gcd10p-Gcd14p nuclear complex is required for 1-methyladenosine modification and maturation of initiator methionyl-tRNA. Genes Dev 12(23):3650-62 SGD PMID 9851972
- Jump up ↑ Anderson J, et al. (2000) The Gcd10p/Gcd14p complex is the essential two-subunit tRNA(1-methyladenosine) methyltransferase of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 97(10):5173-8 SGD PMID 10779558
- Jump up ↑ Hinnebusch A (1992) General and Pathway-specific Regulatory Mechanisms Controlling the Synthesis of Amino Acid Biosynthetic Enzymes in Saccharomyces cerevisiae. Pp. 319-414 in The Molecular and Cellular Biology of the Yeast Saccharomyces: Gene Expression, edited by Jones EW, Pringle JR and Broach JR. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press SGD PMID
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