YJL080C

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Systematic name YJL080C
Gene name SCP160
Aliases
Feature type ORF, Verified
Coordinates Chr X:289226..285558
Primary SGDID S000003616


Description of YJL080C: Essential RNA-binding G protein effector of mating response pathway, mainly associated with nuclear envelope and ER, interacts in mRNA-dependent manner with translating ribosomes via multiple KH domains, similar to vertebrate vigilins[1][2][3][4]




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References

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  1. Baum S, et al. (2004) Asc1p, a WD40-domain containing adaptor protein, is required for the interaction of the RNA-binding protein Scp160p with polysomes. Biochem J 380(Pt 3):823-30 SGD PMID 15012629
  2. Cortes A, et al. (2003) Analysing the contribution of nucleic acids to the structure and properties of centric heterochromatin. Genetica 117(2-3):117-25 SGD PMID 12723691
  3. Guo M, et al. (2003) The yeast G protein alpha subunit Gpa1 transmits a signal through an RNA binding effector protein Scp160. Mol Cell 12(2):517-24 SGD PMID 14536090
  4. Lang BD and Fridovich-Keil JL (2000) Scp160p, a multiple KH-domain protein, is a component of mRNP complexes in yeast. Nucleic Acids Res 28(7):1576-84 SGD PMID 10710424

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