YJL041W

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Systematic name YJL041W
Gene name NSP1
Aliases
Feature type ORF, Verified
Coordinates Chr X:365784..368373
Primary SGDID S000003577


Description of YJL041W: FG-nucleoporin component of central core of the nuclear pore complex (NPC); also part of the NPC nuclear basket; contributes directly to nucleocytoplasmic transport and maintenance of the NPC permeability barrier; found in stable complex with Nup82p, Gle2p and two other FG-nucleoporins (Nup159p and Nup116p); also found in stable complex with Nic96p and two other FG-nucleoproteins (Nup49p and Nup57p)[1][2][3][4][5][6][7][8][9][10][11]




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References

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  1. Jump up Bailer SM, et al. (2001) The Nsp1p carboxy-terminal domain is organized into functionally distinct coiled-coil regions required for assembly of nucleoporin subcomplexes and nucleocytoplasmic transport. Mol Cell Biol 21(23):7944-55 SGD PMID 11689687
  2. Jump up Fahrenkrog B, et al. (1998) Molecular architecture of the yeast nuclear pore complex: localization of Nsp1p subcomplexes. J Cell Biol 143(3):577-88 SGD PMID 9813081
  3. Jump up Frey S and Gorlich D (2009) FG/FxFG as well as GLFG repeats form a selective permeability barrier with self-healing properties. EMBO J 28(17):2554-67 SGD PMID 19680227
  4. Jump up Grosshans H, et al. (2001) Biogenesis of the signal recognition particle (SRP) involves import of SRP proteins into the nucleolus, assembly with the SRP-RNA, and Xpo1p-mediated export. J Cell Biol 153(4):745-62 SGD PMID 11352936
  5. Jump up Hurt EC (1988) A novel nucleoskeletal-like protein located at the nuclear periphery is required for the life cycle of Saccharomyces cerevisiae. EMBO J 7(13):4323-34 SGD PMID 3072197
  6. Jump up Jovanovic-Talisman T, et al. (2009) Artificial nanopores that mimic the transport selectivity of the nuclear pore complex. Nature 457(7232):1023-7 SGD PMID 19098896
  7. Jump up Lutzmann M, et al. (2005) Reconstitution of Nup157 and Nup145N into the Nup84 complex. J Biol Chem 280(18):18442-51 SGD PMID 15741174
  8. Jump up Nehrbass U, et al. (1990) NSP1: a yeast nuclear envelope protein localized at the nuclear pores exerts its essential function by its carboxy-terminal domain. Cell 61(6):979-89 SGD PMID 2112428
  9. Jump up Patel SS, et al. (2007) Natively unfolded nucleoporins gate protein diffusion across the nuclear pore complex. Cell 129(1):83-96 SGD PMID 17418788
  10. Jump up Sharma K, et al. (1996) Yeast nucleoporin mutants are defective in pre-tRNA splicing. Mol Cell Biol 16(1):294-301 SGD PMID 8524308
  11. Jump up Strawn LA, et al. (2004) Minimal nuclear pore complexes define FG repeat domains essential for transport. Nat Cell Biol 6(3):197-206 SGD PMID 15039779

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