YJL013C

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Systematic name YJL013C
Gene name MAD3
Aliases
Feature type ORF, Verified
Coordinates Chr X:411040..409493
Primary SGDID S000003550


Description of YJL013C: Subunit of the spindle-assembly checkpoint complex, which delays anaphase onset in cells with defects in mitotic spindle assembly; pseudosubstrate inhibitor of APC(Cdc20), the anaphase promoting complex involved in securin (Pds1p) turnover[1][2]




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References

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  1. Burton JL and Solomon MJ (2007) Mad3p, a pseudosubstrate inhibitor of APCCdc20 in the spindle assembly checkpoint. Genes Dev 21(6):655-67 SGD PMID 17369399
  2. Hardwick KG, et al. (2000) MAD3 encodes a novel component of the spindle checkpoint which interacts with Bub3p, Cdc20p, and Mad2p. J Cell Biol 148(5):871-82 SGD PMID 10704439

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