YIR025W
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| Systematic name | YIR025W |
| Gene name | MND2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr IX:403659..404765 |
| Primary SGDID | S000001464 |
Description of YIR025W: Subunit of the anaphase-promoting complex (APC); necessary for maintaining sister chromatid cohesion in prophase I of meiosis by inhibiting premature ubiquitination and subsequent degradation of substrates by the APC(Ama1) ubiquitin ligase[1][2][3]
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References
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- ↑ Hall MC, et al. (2003) Mnd2 and Swm1 are core subunits of the Saccharomyces cerevisiae anaphase-promoting complex. J Biol Chem 278(19):16698-705 SGD PMID 12609981
- ↑ Rabitsch KP, et al. (2001) A screen for genes required for meiosis and spore formation based on whole-genome expression. Curr Biol 11(13):1001-9 SGD PMID 11470404
- ↑ Torres MP and Borchers CH (2007) Mitotic Phosphorylation of the Anaphase-promoting Complex Inhibitory Subunit Mnd2 Is Necessary for Efficient Progression through Meiosis I. J Biol Chem 282(24):17351-62 SGD PMID 17459880
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