YIL132C

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Systematic name YIL132C
Gene name CSM2
Aliases
Feature type ORF, Verified
Coordinates Chr IX:100501..99860
Primary SGDID S000001394


Description of YIL132C: Component of the Shu complex, which promotes error-free DNA repair; Shu complex mediates inhibition of Srs2p function; structural analysis reveals a similar DNA-binding region in both Psy3p and Csm2p and that both regions work together to form a single DNA binding site; required for accurate chromosome segregation during meiosis[1][2][3][4][5]




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Community Commentary

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DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically higher expression in sulfur limited chemostat cultures versus sulfur excess. [6] [7]





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References

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  1. Ball LG, et al. (2009) The yeast Shu complex couples error-free post-replication repair to homologous recombination. Mol Microbiol 73(1):89-102 SGD PMID 19496932
  2. Bernstein KA, et al. (2011) The Shu complex, which contains Rad51 paralogues, promotes DNA repair through inhibition of the Srs2 anti-recombinase. Mol Biol Cell 22(9):1599-607 SGD PMID 21372173
  3. Mankouri HW, et al. (2007) Shu proteins promote the formation of homologous recombination intermediates that are processed by sgs1-rmi1-top3. Mol Biol Cell 18(10):4062-73 SGD PMID 17671161
  4. Rabitsch KP, et al. (2001) A screen for genes required for meiosis and spore formation based on whole-genome expression. Curr Biol 11(13):1001-9 SGD PMID 11470404
  5. Tao Y, et al. (2012) Structural analysis of Shu proteins reveals a DNA-binding role essential for resisting damage. J Biol Chem () SGD PMID 22465956
  6. Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
  7. submitted by Viktor Boer on 2003-07-25

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