YIL090W
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| Systematic name | YIL090W |
| Gene name | ICE2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr IX:193595..195070 |
| Primary SGDID | S000001352 |
Description of YIL090W: Integral ER membrane protein with type-III transmembrane domains; required for maintenance of ER zinc homeostasis; necessary for efficient targeting of Trm1p tRNA methyltransferase to inner nuclear membrane; mutations cause defects in cortical ER morphology in both the mother and daughter cells[1][2][3]
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References
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- ↑ Estrada de Martin P, et al. (2005) Ice2p is important for the distribution and structure of the cortical ER network in Saccharomyces cerevisiae. J Cell Sci 118(Pt 1):65-77 SGD PMID 15585575
- ↑ Murthi A and Hopper AK (2005) Genome-wide screen for inner nuclear membrane protein targeting in Saccharomyces cerevisiae: roles for N-acetylation and an integral membrane protein. Genetics 170(4):1553-60 SGD PMID 15911569
- ↑ North M, et al. (2012) Genome-Wide Functional Profiling Identifies Genes and Processes Important for Zinc-Limited Growth of Saccharomyces cerevisiae. PLoS Genet 8(6):e1002699 SGD PMID 22685415
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