YIL084C

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Systematic name YIL084C
Gene name SDS3
Aliases
Feature type ORF, Verified
Coordinates Chr IX:203259..202276
Primary SGDID S000001346


Description of YIL084C: Component of the Rpd3p/Sin3p deacetylase complex required for its structural integrity and catalytic activity, involved in transcriptional silencing and required for sporulation; cells defective in SDS3 display pleiotropic phenotypes[1][2][3]




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References

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  1. Lechner T, et al. (2000) Sds3 (suppressor of defective silencing 3) is an integral component of the yeast Sin3[middle dot]Rpd3 histone deacetylase complex and is required for histone deacetylase activity. J Biol Chem 275(52):40961-6 SGD PMID 11024051
  2. Vannier D, et al. (1996) Evidence that the transcriptional regulators SIN3 and RPD3, and a novel gene (SDS3) with similar functions, are involved in transcriptional silencing in S. cerevisiae. Genetics 144(4):1343-53 SGD PMID 8978024
  3. Vannier D, et al. (2001) A role for Sds3p, a component of the Rpd3p/Sin3p deacetylase complex, in maintaining cellular integrity in Saccharomyces cerevisiae. Mol Genet Genomics 265(3):560-8 SGD PMID 11405640

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