YIL049W

From SGD-Wiki
Jump to: navigation, search

Share your knowledge...Edit this entry! <protect>

Systematic name YIL049W
Gene name DFG10
Aliases
Feature type ORF, Verified
Coordinates Chr IX:260158..260919
Primary SGDID S000001311


Description of YIL049W: Probable polyprenol reductase that catalyzes conversion of polyprenol to dolichol, the precursor for N-glycosylation; involved in filamentous growth; mutations in human ortholog SRD5A3 confer CDG (Congenital Disorders of Glycosylation)[1][2]




</protect>

Community Commentary

About Community Commentary. Please share your knowledge!




<protect>

References

See Help:References on how to add references

  1. Cantagrel V, et al. (2010) SRD5A3 is required for converting polyprenol to dolichol and is mutated in a congenital glycosylation disorder. Cell 142(2):203-17 SGD PMID 20637498
  2. Mosch HU and Fink GR (1997) Dissection of filamentous growth by transposon mutagenesis in Saccharomyces cerevisiae. Genetics 145(3):671-84 SGD PMID 9055077

See Help:Categories on how to add the wiki page for this gene to a Category </protect>