YIL030C

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Systematic name YIL030C
Gene name SSM4
Aliases DOA10, KIS3
Feature type ORF, Verified
Coordinates Chr IX:300009..296050
Primary SGDID S000001292


Description of YIL030C: Ubiquitin-protein ligase involved in ER-associated protein degradation; located in the ER/nuclear envelope; ssm4 mutation suppresses mRNA instability caused by an rna14 mutation[1][2]




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References

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  1. Mandart E, et al. (1994) Inactivation of SSM4, a new Saccharomyces cerevisiae gene, suppresses mRNA instability due to rna14 mutations. Mol Gen Genet 245(3):323-33 SGD PMID 7816042
  2. Swanson R, et al. (2001) A conserved ubiquitin ligase of the nuclear envelope/endoplasmic reticulum that functions in both ER-associated and Matalpha2 repressor degradation. Genes Dev 15(20):2660-74 SGD PMID 11641273

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