YIL020C
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| Systematic name | YIL020C |
| Gene name | HIS6 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr IX:314820..314035 |
| Primary SGDID | S000001282 |
Description of YIL020C: Phosphoribosyl-5-amino-1-phosphoribosyl-4-imidazolecarboxiamide isomerase, catalyzes the fourth step in histidine biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts[1][2][3]
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References
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- ↑ Alifano P, et al. (1996) Histidine biosynthetic pathway and genes: structure, regulation, and evolution. Microbiol Rev 60(1):44-69 SGD PMID 8852895
- ↑ Fani R, et al. (1997) Paralogous histidine biosynthetic genes: evolutionary analysis of the Saccharomyces cerevisiae HIS6 and HIS7 genes. Gene 197(1-2):9-17 SGD PMID 9332345
- ↑ Pearce DA and Sherman F (1999) Toxicity of copper, cobalt, and nickel salts is dependent on histidine metabolism in the yeast Saccharomyces cerevisiae. J Bacteriol 181(16):4774-9 SGD PMID 10438744
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