YIL002C

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Systematic name YIL002C
Gene name INP51
Aliases SJL1
Feature type ORF, Verified
Coordinates Chr IX:353431..350591
Primary SGDID S000001264


Description of YIL002C: Phosphatidylinositol 4,5-bisphosphate 5-phosphatase, synaptojanin-like protein with an N-terminal Sac1 domain, plays a role in phosphatidylinositol 4,5-bisphosphate homeostasis and in endocytosis; null mutation confers cold-tolerant growth[1][2][3]




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References

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  1. Hughes WE, et al. (2000) Sac phosphatase domain proteins. Biochem J 350 Pt 2():337-52 SGD PMID 10947947
  2. Singer-Kruger B, et al. (1998) Synaptojanin family members are implicated in endocytic membrane traffic in yeast. J Cell Sci 111 ( Pt 22):3347-56 SGD PMID 9788876
  3. Stolz LE, et al. (1998) INP51, a yeast inositol polyphosphate 5-phosphatase required for phosphatidylinositol 4,5-bisphosphate homeostasis and whose absence confers a cold-resistant phenotype. J Biol Chem 273(19):11852-61 SGD PMID 9565610

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