YHR204W
Share your knowledge...Edit this entry! <protect>
| Systematic name | YHR204W |
| Gene name | MNL1 |
| Aliases | HTM1 |
| Feature type | ORF, Verified |
| Coordinates | Chr VIII:506319..508709 |
| Primary SGDID | S000001247 |
Description of YHR204W: Alpha-1,2-specific exomannosidase of the endoplasmic reticulum; in complex with Pdi1p, generates a Man7GlcNac2 oligosaccharide signal on glycoproteins destined for ubiquitin-proteasome degradation[1][2][3][4]
</protect>
Contents
Community Commentary
About Community Commentary. Please share your knowledge!
<protect>
References
See Help:References on how to add references
- ↑ Clerc S, et al. (2009) Htm1 protein generates the N-glycan signal for glycoprotein degradation in the endoplasmic reticulum. J Cell Biol 184(1):159-72 SGD PMID 19124653
- ↑ Gauss R, et al. (2011) A complex of pdi1p and the mannosidase htm1p initiates clearance of unfolded glycoproteins from the endoplasmic reticulum. Mol Cell 42(6):782-93 SGD PMID 21700223
- ↑ Jakob CA, et al. (2001) Htm1p, a mannosidase-like protein, is involved in glycoprotein degradation in yeast. EMBO Rep 2(5):423-30 SGD PMID 11375935
- ↑ Nakatsukasa K, et al. (2001) Mnl1p, an alpha -mannosidase-like protein in yeast Saccharomyces cerevisiae, is required for endoplasmic reticulum-associated degradation of glycoproteins. J Biol Chem 276(12):8635-8 SGD PMID 11254655
See Help:Categories on how to add the wiki page for this gene to a Category </protect>
