YHR194W

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Systematic name YHR194W
Gene name MDM31
Aliases
Feature type ORF, Verified
Coordinates Chr VIII:488657..490396
Primary SGDID S000001237


Description of YHR194W: Mitochondrial protein that may have a role in phospholipid metabolism; inner membrane protein with similarity to Mdm32p; required for normal mitochondrial morphology and inheritance; interacts genetically with MMM1, MMM2, MDM10, MDM12, and MDM34[1][2]




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Community Commentary

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Other

mitochondrial biogenesis

Mdm31p (as well as Mdm32p) seems to play a role in regulation of mitochondrial cation homeostasis and mitochondrial volume. [3] [4]





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References

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  1. Dimmer KS, et al. (2005) Mdm31 and Mdm32 are inner membrane proteins required for maintenance of mitochondrial shape and stability of mitochondrial DNA nucleoids in yeast. J Cell Biol 168(1):103-15 SGD PMID 15631992
  2. Tamura Y, et al. (2012) Role for two conserved intermembrane space proteins, Ups1p and Up2p, in intra-mitochondrial phospholipid trafficking. J Biol Chem () SGD PMID 22403410
  3. Kucejova B, et al. (2005) A screen for nigericin-resistant yeast mutants revealed genes controlling mitochondrial volume and mitochondrial cation homeostasis. Genetics 171(2):517-26 SGD PMID 16020778
  4. submitted by Lubomir Tomaska on 2005-12-21

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