YHR154W
Share your knowledge...Edit this entry! <protect>
| Systematic name | YHR154W |
| Gene name | RTT107 |
| Aliases | ESC4 |
| Feature type | ORF, Verified |
| Coordinates | Chr VIII:402966..406178 |
| Primary SGDID | S000001197 |
Description of YHR154W: Protein implicated in Mms22-dependent DNA repair during S phase; involved in recruiting the SMC5/6 complex to double-strand breaks; DNA damage induces phosphorylation by Mec1p at one or more SQ/TQ motifs; interacts with Mms22p and Slx4p; has four BRCT domains; has a role in regulation of Ty1 transposition[1][2][3][4][5]
</protect>
Contents
[hide]Community Commentary
About Community Commentary. Please share your knowledge!
<protect>
References
See Help:References on how to add references
- Jump up ↑ Baldwin EL, et al. (2005) Mms22p protects Saccharomyces cerevisiae from DNA damage induced by topoisomerase II. Nucleic Acids Res 33(3):1021-30 SGD PMID 15718301
- Jump up ↑ Leung GP, et al. (2011) Rtt107 is required for recruitment of the SMC5/6 complex to DNA double-strand breaks. J Biol Chem () SGD PMID 21642432
- Jump up ↑ Roberts TM, et al. (2006) Slx4 regulates DNA damage checkpoint-dependent phosphorylation of the BRCT domain protein Rtt107/Esc4. Mol Biol Cell 17(1):539-48 SGD PMID 16267268
- Jump up ↑ Rouse J (2004) Esc4p, a new target of Mec1p (ATR), promotes resumption of DNA synthesis after DNA damage. EMBO J 23(5):1188-97 SGD PMID 14988729
- Jump up ↑ Scholes DT, et al. (2001) Multiple regulators of Ty1 transposition in Saccharomyces cerevisiae have conserved roles in genome maintenance. Genetics 159(4):1449-65 SGD PMID 11779788
See Help:Categories on how to add the wiki page for this gene to a Category </protect>
