YHR133C

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Systematic name YHR133C
Gene name NSG1
Aliases
Feature type ORF, Verified
Coordinates Chr VIII:371597..370722
Primary SGDID S000001175


Description of YHR133C: Protein involved in regulation of sterol biosynthesis; specifically stabilizes Hmg2p, one of two HMG-CoA isoenzymes that catalyze the rate-limiting step in sterol biosynthesis; homolog of mammalian INSIG proteins[1]




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References

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  1. Flury I, et al. (2005) INSIG: a broadly conserved transmembrane chaperone for sterol-sensing domain proteins. EMBO J 24(22):3917-26 SGD PMID 16270032

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