YHR120W

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Systematic name YHR120W
Gene name MSH1
Aliases
Feature type ORF, Verified
Coordinates Chr VIII:349574..352453
Primary SGDID S000001162


Description of YHR120W: DNA-binding protein of the mitochondria involved in repair of mitochondrial DNA, has ATPase activity and binds to DNA mismatches; has homology to E. coli MutS; transcription is induced during meiosis[1][2][3]




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References

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  1. Chi NW and Kolodner RD (1994) The effect of DNA mismatches on the ATPase activity of MSH1, a protein in yeast mitochondria that recognizes DNA mismatches. J Biol Chem 269(47):29993-7 SGD PMID 7961999
  2. Meyer C, et al. (2001) Transcription of mutS- and mutL-homologous genes during meiosis in Saccharomyces cerevisiae and identification of a regulatory cis-element for meiotic induction of MSH2. Mol Genet Genomics 265(5):826-36 SGD PMID 11523800
  3. Reenan RA and Kolodner RD (1992) Isolation and characterization of two Saccharomyces cerevisiae genes encoding homologs of the bacterial HexA and MutS mismatch repair proteins. Genetics 132(4):963-73 SGD PMID 1459447

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