YHR050W

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Systematic name YHR050W
Gene name SMF2
Aliases
Feature type ORF, Verified
Coordinates Chr VIII:207654..209303
Primary SGDID S000001092


Description of YHR050W: Divalent metal ion transporter involved in manganese homeostasis; has broad specificity for di-valent and tri-valent metals; post-translationally regulated by levels of metal ions; member of the Nramp family of metal transport proteins[1][2][3]




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References

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  1. Chen XZ, et al. (1999) Yeast SMF1 mediates H(+)-coupled iron uptake with concomitant uncoupled cation currents. J Biol Chem 274(49):35089-94 SGD PMID 10574989
  2. Luk EE and Culotta VC (2001) Manganese superoxide dismutase in Saccharomyces cerevisiae acquires its metal co-factor through a pathway involving the Nramp metal transporter, Smf2p. J Biol Chem 276(50):47556-62 SGD PMID 11602606
  3. Portnoy ME, et al. (2002) The distinct methods by which manganese and iron regulate the Nramp transporters in yeast. Biochem J 362(Pt 1):119-24 SGD PMID 11829747

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