YHR041C
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| Systematic name | YHR041C |
| Gene name | SRB2 |
| Aliases | HRS2, MED20 |
| Feature type | ORF, Verified |
| Coordinates | Chr VIII:189864..189131 |
| Primary SGDID | S000001083 |
Description of YHR041C: Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; general transcription factor involved in telomere maintenance[1][2][3][4][5][6]
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References
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- ↑ Askree SH, et al. (2004) A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proc Natl Acad Sci U S A 101(23):8658-63 SGD PMID 15161972
- ↑ Kim YJ, et al. (1994) A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II. Cell 77(4):599-608 SGD PMID 8187178
- ↑ Kornberg RD (2005) Mediator and the mechanism of transcriptional activation. Trends Biochem Sci 30(5):235-9 SGD PMID 15896740
- ↑ Myers LC, et al. (1998) The Med proteins of yeast and their function through the RNA polymerase II carboxy-terminal domain. Genes Dev 12(1):45-54 SGD PMID 9420330
- ↑ Nonet ML and Young RA (1989) Intragenic and extragenic suppressors of mutations in the heptapeptide repeat domain of Saccharomyces cerevisiae RNA polymerase II. Genetics 123(4):715-24 SGD PMID 2693207
- ↑ Thompson CM, et al. (1993) A multisubunit complex associated with the RNA polymerase II CTD and TATA-binding protein in yeast. Cell 73(7):1361-75 SGD PMID 8324825
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