YHR004C
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| Systematic name | YHR004C |
| Gene name | NEM1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VIII:113094..111754 |
| Primary SGDID | S000001046 |
Description of YHR004C: Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme; regulates nuclear growth by controlling phospholipid biosynthesis, required for normal nuclear envelope morphology and sporulation; homolog of the human protein Dullard[1][2][3]
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References
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- ↑ Kim Y, et al. (2007) A conserved phosphatase cascade that regulates nuclear membrane biogenesis. Proc Natl Acad Sci U S A 104(16):6596-601 SGD PMID 17420445
- ↑ Santos-Rosa H, et al. (2005) The yeast lipin Smp2 couples phospholipid biosynthesis to nuclear membrane growth. EMBO J 24(11):1931-41 SGD PMID 15889145
- ↑ Siniossoglou S, et al. (1998) A novel complex of membrane proteins required for formation of a spherical nucleus. EMBO J 17(22):6449-64 SGD PMID 9822591
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