YHL007C

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Systematic name YHL007C
Gene name STE20
Aliases
Feature type ORF, Verified
Coordinates Chr VIII:97937..95118
Primary SGDID S000000999


Description of YHL007C: Cdc42p-activated signal transducing kinase of the PAK (p21-activated kinase) family; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p[1][2][3][4]




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References

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  1. Jump up Bartholomew CR and Hardy CF (2009) p21-activated kinases Cla4 and Ste20 regulate vacuole inheritance in Saccharomyces cerevisiae. Eukaryot Cell 8(4):560-72 SGD PMID 19218422
  2. Jump up Lin M, et al. (2009) The Cdc42 effectors Ste20, Cla4, and Skm1 down-regulate the expression of genes involved in sterol uptake by a mitogen-activated protein kinase-independent pathway. Mol Biol Cell 20(22):4826-37 SGD PMID 19793923
  3. Jump up Peter M, et al. (1996) Functional analysis of the interaction between the small GTP binding protein Cdc42 and the Ste20 protein kinase in yeast. EMBO J 15(24):7046-59 SGD PMID 9003780
  4. Jump up Song J, et al. (2001) Molecular interactions of the Gbeta binding domain of the Ste20p/PAK family of protein kinases. An isolated but fully functional Gbeta binding domain from Ste20p is only partially folded as shown by heteronuclear NMR spectroscopy. J Biol Chem 276(44):41205-12 SGD PMID 11509560

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