YGR296W

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Systematic name YGR296W
Gene name YRF1-3
Aliases YRF1
Feature type ORF, Verified
Coordinates Chr VII:1084864..1090591
Primary SGDID S000003528


Description of YGR296W: Helicase encoded by the Y' element of subtelomeric regions, highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p[1][2]




Contents

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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [1] [3]





References

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  1. 1.0 1.1 Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  2. Yamada M, et al. (1998) Y'-Help1, a DNA helicase encoded by the yeast subtelomeric Y' element, is induced in survivors defective for telomerase. J Biol Chem 273(50):33360-6 SGD PMID 9837911
  3. submitted by Jeff Ubersax on 2004-01-27

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