YGR278W

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Systematic name YGR278W
Gene name CWC22
Aliases
Feature type ORF, Verified
Coordinates Chr VII:1046731..1048464
Primary SGDID S000003510


Description of YGR278W: Spliceosome-associated protein that is required for pre-mRNA splicing; necessary for Prp2p function at the first catalytic step of splicing; has similarity to S. pombe Cwf22p; CWC22 is an essential protein[1][2]




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References

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  1. Ohi MD, et al. (2002) Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs. Mol Cell Biol 22(7):2011-24 SGD PMID 11884590
  2. Yeh TC, et al. (2011) Splicing factor Cwc22 is required for the function of Prp2 and for the spliceosome to escape from a futile pathway. Mol Cell Biol 31(1):43-53 SGD PMID 20956557

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